• Signs of Hereditary Cancer

  • If you or a close relative* have any of the following, a referral to the Genetic Counseling Clinic may be indicated for you:

    *Close relatives are: parents, children, brothers, sisters, aunts and uncles, nieces, nephews, grandparents, and grandchildren.

    Hereditary Breast and Ovarian Cancer:

    • Invasive breast cancer or DCIS diagnosed at or under age 50
    • Two or more blood-related individuals with breast cancer
    • Male breast cancer
    • Ovarian, fallopian tube, or primary peritoneal cancer at any age
    • Breast cancer and one or more other separate cancers *
    • Breast cancer and large head circumference (57 cm or larger for women, 59 cm or larger for men), and/or mental retardation/autism
    • Breast cancer with Eastern European Jewish ancestry, or Hispanic/Latino ancestry from southern Colorado or northern New Mexico

    *Cancers that accompany breast cancer in inherited syndromes include: a second new breast cancer, brain, thyroid, pancreatic, & endometrial cancers; lymphoma/leukemia; and adrenal cortical or choroid plexus carcinomas.

    Hereditary Colorectal Cancer:

    • Colorectal OR uterine cancer diagnosed  under age 60
    • Two or more separate colorectal cancers in the same person
    • Three or more blood related individuals with colorectal or uterine cancer
    • Colorectal cancer or uterine cancer and a personal or family history of other cancers*                                                                                              
    • Ten or more cumulative gastrointestinal adenomas or hyperplastic polyps
    • Hamartomas, juvenile polyps, Peutz-Jeghers polyps
    • Pathology of the colorectal tumor shows microsatellite instability or  evidence of a mismatch repair defect.

    *Cancers/tumors that accompany colorectal cancer in inherited syndromes include: uterine, ovarian, stomach, small intestine, pancreatic, urinary tract cancers, brain tumors, sebaceous adenomas and keratocanthomas.

    Other hereditary cancer syndromes:

    • An identified inherited/genetic syndrome
    • An individual with bilateral or multiple primary cancers or brain tumors
    • An individual diagnosed with cancer at an unusually young age
    • Three or more blood related family members with the same type of cancer
    • Rare cancers such as: medullary thyroid cancer, adrenocortical carcinoma, pheochromocytoma, and paraganglioma
Search: Current Site All Sites